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PRP (Platelet-Rich Plasma) and BMAC (Bone Marrow Aspirate Concentrate) are two cutting-edge orthobiologic treatments used to reduce pain, promote healing, and delay or avoid surgery—especially in joint, tendon, and cartilage conditions If you are experiencing knee pain, you may be considering platelet rich plasma (PRP) knee injections as a possible treatment option for joint pain. PRP injections are becoming an increasingly popular choice to decrease pain in health care, and there is a good reason why. It is a common alternative to corticosteroid injections.